Omecamtiv mecarbil ( CK-1827452 )

产品货号. M16353 CAS No. 873697-71-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Omecamtiv mecarbil
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Omecamtiv mecarbil (CK-1827452) is the first potent cardiac myosin activator that can specifically activate the cardiac myosin S1 domain but not other muscle myosins.
产品描述

Omecamtiv mecarbil (CK-1827452) is the first potent cardiac myosin activator that can specifically activate the cardiac myosin S1 domain but not other muscle myosins. In clinical trials, omecamtiv mecarbil has been considered as a promising therapeutic approach to treat systolic heart failure1.
同义词

CK-1827452
通路

Endocrinology/Hormones
靶点

ATPase
受体

ATPase
研究领域

Cardiovascular Disease
适应症

——

CAS Number

873697-71-3
分子量

401.43
分子式

C20H24FN5O3
纯度

>98%(HPLC)
溶解度

Ethanol: 6 mg/mL (14.94 mM); DMSO: 80 mg/mL (199.28 mM)
SMILES

O=C(N1CCN(CC2=CC=CC(NC(NC3=CC=C(C)N=C3)=O)=C2F)CC1)OC
化学全称

methyl 4-(2-fluoro-3-(3-(6-methylpyridin-3-yl)ureido)benzyl)piperazine-1-carboxylate

1.Anderson RL, et al. Mol Bio Cell, 2005, 16.

计算器

产品手册

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